What we analyse

The full scope, including where it stops.

Everything below is analysis of data you already have. We do not run wet lab work, and we do not resell sequencing.

Single-cell / single-nucleus RNA-seq

From count matrix to annotated populations

Accepts Cell Ranger output, an AnnData .h5ad, a Seurat object, or a plain matrix.

  • Empty-droplet and doublet handling, ambient RNA correction
  • Per-dataset QC thresholds with the reasoning shown
  • Clustering across a resolution range, not a single guess
  • Automated plus manual cell-type annotation, verified against markers
  • Differential expression aggregated to sample level for group comparisons
  • Gene-set and pathway scoring
Spatial transcriptomics

Sequencing-based and imaging-based

Visium and Visium HD, Stereo-seq, Xenium, CosMx, MERFISH.

  • Spot and cell QC, tissue detection, image registration
  • Spatial domain identification
  • Spatially variable genes
  • Deconvolution against a matched single-cell reference
  • Neighbourhood and co-localisation statistics
  • Overlays on the H&E or immunofluorescence image
Bulk RNA-seq

Differential expression that survives review

  • Intake from counts, or from FASTQ via a standard quantification pipeline
  • Design and contrasts written down before testing
  • Covariate and batch handling
  • GO, KEGG and GSEA enrichment
  • Volcano, heatmap, PCA and per-gene panels as vector files
Cross-cutting

Modules that sit on top of any of the above

  • Multi-sample integration with an over-correction check
  • Differential abundance between conditions
  • Trajectory and pseudotime
  • Cell–cell communication
  • CITE-seq and multiome (RNA + ATAC) joint analysis
  • Re-analysis of a public dataset alongside yours

Out of scope

What we will tell you we cannot do.

Wet lab work

No sample preparation, library construction or sequencing. If you need those, keep your provider — we work with whatever they return.

Clinical or diagnostic reporting

Our output is for research. We do not issue diagnostic interpretations and nothing we deliver is a medical device.

A conclusion you have already chosen

If the data does not support the comparison, that is what the report will say. It is cheaper to hear it from us than from a reviewer.

Not sure it fits? Send the data description and the question. If it is outside what we do well, we will say so in the reply rather than quote for it.

Tell us what you have.

Data type, rough scale, and the comparison you want to make. That is enough for a scope and a price.